KEGG   Homo sapiens (human): 54760
Entry
54760             CDS       T01001                                 
Symbol
PCSK4, PC4, SPC5
Name
(RefSeq) proprotein convertase subtilisin/kexin type 4
  KO
K08671  proprotein convertase subtilisin/kexin type 4 [EC:3.4.21.-]
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    54760 (PCSK4)
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:hsa03110]
    54760 (PCSK4)
   04131 Membrane trafficking [BR:hsa04131]
    54760 (PCSK4)
Peptidases and inhibitors [BR:hsa01002]
 Serine peptidases
  Family S8: subtilisin family
   54760 (PCSK4)
Chaperones and folding catalysts [BR:hsa03110]
 Intramolecular chaperones
  Subtilisin family
   54760 (PCSK4)
Membrane trafficking [BR:hsa04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Acrosomal exocytosis proteins
    54760 (PCSK4)
SSDB
Motif
Pfam: Peptidase_S8 P_proprotein S8_pro-domain
Other DBs
NCBI-GeneID: 54760
NCBI-ProteinID: NP_060043
OMIM: 600487
HGNC: 8746
Ensembl: ENSG00000115257
UniProt: Q6UW60 A0A140VJQ9
Position
19:complement(1481428..1490876)
AA seq 755 aa
MRPAPIALWLRLVLALALVRPRAVGWAPVRAPIYVSSWAVQVSQGNREVERLARKFGFVN
LGPIFPDGQYFHLRHRGVVQQSLTPHWGHRLHLKKNPKVQWFQQQTLQRRVKRSVVVPTD
PWFSKQWYMNSEAQPDLSILQAWSQGLSGQGIVVSVLDDGIEKDHPDLWANYDPLASYDF
NDYDPDPQPRYTPSKENRHGTRCAGEVAAMANNGFCGVGVAFNARIGGVRMLDGTITDVI
EAQSLSLQPQHIHIYSASWGPEDDGRTVDGPGILTREAFRRGVTKGRGGLGTLFIWASGN
GGLHYDNCNCDGYTNSIHTLSVGSTTQQGRVPWYSEACASTLTTTYSSGVATDPQIVTTD
LHHGCTDQHTGTSASAPLAAGMIALALEANPFLTWRDMQHLVVRASKPAHLQAEDWRTNG
VGRQVSHHYGYGLLDAGLLVDTARTWLPTQPQRKCAVRVQSRPTPILPLIYIRENVSACA
GLHNSIRSLEHVQAQLTLSYSRRGDLEISLTSPMGTRSTLVAIRPLDVSTEGYNNWVFMS
THFWDENPQGVWTLGLENKGYYFNTGTLYRYTLLLYGTAEDMTARPTGPQVTSSACVQRD
TEGLCQACDGPAYILGQLCLAYCPPRFFNHTRLVTAGPGHTAAPALRVCSSCHASCYTCR
GGSPRDCTSCPPSSTLDQQQGSCMGPTTPDSRPRLRAAACPHHRCPASAMVLSLLAVTLG
GPVLCGMSMDLPLYAWLSRARATPTKPQVWLPAGT
NT seq 2268 nt   +upstreamnt  +downstreamnt
atgcggcccgccccgattgcgctgtggctgcgcctggtcttggccctggcccttgtccgc
ccccgggctgtggggtgggccccggtccgagcccccatctatgtcagcagctgggccgtc
caggtgtcccagggtaaccgggaggtcgagcgcctggcacgcaaattcggcttcgtcaac
ctggggccgatcttccctgacgggcagtactttcacctgcggcaccggggcgtggtccag
cagtccctgaccccgcactggggccaccgcctgcacctgaagaaaaaccccaaggtgcag
tggttccagcagcagacgctgcagcggcgggtgaaacgctctgtcgtggtgcccacggac
ccctggttctccaagcagtggtacatgaacagcgaggcccaaccagacctgagcatcctg
caggcctggagtcaggggctgtcaggccagggcatcgtggtctctgtgctggacgatggc
atcgagaaggaccacccggacctctgggccaactacgaccccctggccagctatgacttc
aatgactacgacccggacccccagccccgctacacccccagcaaagagaaccggcacggg
acccgctgtgctggggaggtggccgcgatggccaacaatggcttctgtggtgtgggggtc
gctttcaacgcccgaatcggaggcgtacggatgctggacggtaccatcaccgatgtcatc
gaggcccagtcgctgagcctgcagccgcagcacatccacatttacagcgccagctggggt
cccgaggacgacggccgcacggtggacggccccggcatcctcacccgcgaggccttccgg
cgtggtgtgaccaagggccgcggcgggctgggcacgctcttcatctgggcctcgggcaac
ggcggcctgcactacgacaactgcaactgcgacggctacaccaacagcatccacacgctt
tccgtgggcagcaccacccagcagggccgcgtgccctggtacagcgaagcctgcgcctcc
accctcaccaccacctacagcagcggcgtggccaccgacccccagatcgtcaccacggac
ctgcatcacgggtgcacagaccagcacacgggcacctcggcctcagccccactggcggcc
ggcatgatcgccctagcgctggaggccaacccgttcctgacgtggagagacatgcagcac
ctggtggtccgcgcgtccaagccggcgcacctgcaggccgaggactggaggaccaacggc
gtggggcgccaagtgagccatcactacggatacgggctgctggacgccgggctgctggtg
gacaccgcccgcacctggctgcccacccagccgcagaggaagtgcgccgtccgggtccag
agccgccccacccccatcctgccgctgatctacatcagggaaaacgtatcggcctgcgcc
ggcctccacaactccatccgctcgctggagcacgtgcaggcgcagctgacgctgtcctac
agccggcgcggagacctggagatctcgctcaccagccccatgggcacgcgctccacactc
gtggccatacgacccttggacgtcagcactgaaggctacaacaactgggtcttcatgtcc
acccacttctgggatgagaacccacagggcgtgtggaccctgggcctagagaacaagggc
tactatttcaacacggggacgttgtaccgctacacgctgctgctctatgggacggccgag
gacatgacagcgcggcctacaggcccccaggtgaccagcagcgcgtgtgtgcagcgggac
acagaggggctgtgccaggcgtgtgacggccccgcctacatcctgggacagctctgcctg
gcctactgccccccgcggttcttcaaccacacaaggctggtgaccgctgggcctgggcac
acggcggcgcccgcgctgagggtctgctccagctgccatgcctcctgctacacctgccgc
ggcggctccccgagggactgcacctcctgtcccccatcctccacgctggaccagcagcag
ggctcctgcatgggacccaccacccccgacagccgcccccggcttagagctgccgcctgt
ccccaccaccgctgcccagcctcggccatggtgctgagcctcctggccgtgaccctcgga
ggccccgtcctctgcggcatgtccatggacctcccactatacgcctggctctcccgtgcc
agggccacccccaccaaaccccaggtctggctgccagctggaacctga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (46)   
   KEGG ORTHOLOGY (1)   
   RefGene (31)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (9)   
   OC (1)   
Protein sequence (53)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (50)   
DNA sequence (72)   
   RefSeq(nuc) (50)   
   GenBank (11)   
   EMBL (11)   
Protein domain (3)   
   Pfam (3)   
All databases (180)   

Download RDF
DBGET integrated database retrieval system